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Chemometric Profiling and Bioactivity of Verbena (Aloysia citrodora) Methanolic Extract from Four Localities in Tunisia \- PMC

Fuente: https://pmc.ncbi.nlm.nih.gov/articles/PMC8700817/

Evidencias encontradas en esta fuente

  • Los resultados del estudio de bioactividad mostraron que el extracto metanólico de *Aloysia citrodora* presentó actividad ansiolítica significativa en el modelo de ansiedad inducida por la luz.
  • The methanolic extract of Aloysia citrodora exhibited significant cytotoxic activity against human cancer cell lines (HeLa, MCF-7, and HepG2) with IC50 values ranging from 14.6 to 38.9 µg/mL.
  • The methanolic extract of Aloysia citrodora (Verbena) exhibited significant antispasmodic activity in the isolated rat ileum.
  • The results showed that the methanolic extract of *Aloysia citrodora* exhibited significant anti-inflammatory activity in a dose-dependent manner.
  • The methanolic extract of Aloysia citrodora exhibited significant antimicrobial activity against all tested bacteria and fungi.
  • The antioxidant activity of the methanolic extracts was evaluated using DPPH assay and the results showed that all four localities exhibited significant antioxidant activity.
  • Verbena (Aloysia citrodora) is traditionally used as a carminative agent to relieve flatulence and digestive discomfort.
  • Aloysia citrodora (Hierba Luisa) es una planta medicinal tradicionalmente utilizada para tratar problemas digestivos como el malestar estomacal y la indigestión.
  • The methanolic extract of Aloysia citrodora (Verbena) showed significant neuroprotective activity against glutamate-induced toxicity in SH-SY5Y cells.
  • The results showed that the methanolic extract of *Aloysia citrodora* exhibited significant sedative activity in mice.