Apple (Malus domestica Borkh) leaves attenuate indomethacin-induced gastric ulcer in rats

Fuente: https://pubmed.ncbi.nlm.nih.gov/36736281/

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The present work aimed to annotate the secondary metabolites from a butanol fraction of apple leaves (BLE), evaluate the gastro-protective and healing effects of this fraction against indomethacin-induced gastric ulcers in rats and to identify its mechanism of action. BLE (100, and 200 mg/kg) was orally administered in rats as an acute treatment against indomethacin-induced gastric ulcer in comparison with famotidine as reference anti-ulcer drug.

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